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Prednisone may be added to increase calciuresis if a bisphosphonate is not available

doi: 10.1016/j.trsl.2017.10.004

Musculoskeletal improvements in strength, range of motion, and pain reduction typically follow over weeks 3 through 6

Shin et al., 2005) and a reduced glutamate clearance capacity in the R6/2 mice could only be revealed by treatment with EAAT inhibitors or glutamate (Behrens et al., 2009)